Medical Image – Based Computational Model of Pulsatile Flow in Saccular Aneurisms
نویسندگان
چکیده
Saccular aneurisms, swelling of a blood vessel, are investigated in order (i) to estimate the development risk of the wall lesion, before and after intravascular treatment, assuming that the pressure is the major factor, and (ii) to better plan medical interventions. Numerical simulations, using the finite element method, are performed in three-dimensional aneurisms. Computational meshes are derived from medical imaging data to take into account both between-subject and within-subject anatomical variability of the diseased vessel segment. The 3D reconstruction is associated with a faceted surface. A geometrical model is then obtained to be finally meshed for a finite element use. The pulsatile flow of incompressible Newtonian blood is illustrated by numerical simulations carried out in two saccular aneurism types, a sideand a terminal-aneurism. High pressure zones are observed in the aneurism cavity, especially in the terminal one. Mathematics Subject Classification. 68U05, 68U10, 76D05, 35Q30, 65N30.
منابع مشابه
From arteriographies to computational flow in saccular aneurisms: the INRIA experience
Saccular aneurisms illustrate usefulness and possible techniques of image-based modeling of flow in diseased vessels. Aneurism flow is investigated in order to estimate the rupture risk, assuming that the pressure is the major factor and that high-pressure zones are correlated to within-wall strong-stress concentrations. Computational flow is also aimed at providing additional arguments for the...
متن کامل2D Computational Fluid Dynamic Modeling of Human Ventricle System Based on Fluid-Solid Interaction and Pulsatile Flow
Many diseases are related to cerebrospinal .uid (CSF) hydrodynamics. Therefore, understanding the hydrodynamics of CSF .ow and intracranial pressure is helpful for obtaining deeper knowledge of pathological processes and providing better treatments. Furthermore, engineering a reliable computational method is promising approach for fabricating in vitro models which is essential for inventing gen...
متن کاملAn advection-diffusion multi-layer porous model for stent drug delivery in coronary arteries
Arterial drug concentration distribution determines local toxicity. The safety issues dealt with Drug-Eluting Stents (DESs) reveal the needs for investigation about the effective factors contributing to fluctuations in arterial drug uptake. The current study focused on the importance of hypertension as an important and controversial risk factor among researchers on the efficacy of Heparin-Eluti...
متن کاملEffect of six non-Newtonian viscosity models on hemodynamic parameters of pulsatile blood flow in stenosed artery
A numerical study of hemodynamic parameters of pulsatile blood flow is presented in a stenotic artery with A numerical study of hemodynamic parameters of pulsatile blood flow is presented in a stenotic artery with non-Newtonian models using ADINA. Blood flow was considered laminar, and the arterial wall was considered rigid. Studied stenosis severities were 30, 50, and 70% of the cross-section...
متن کاملStudy of Pulsatile Non-Newtonian Blood Flow Through Abdominal Aorta and Renal Arteries Incorporating Fluid- Structure Interaction
Background: The interaction between the blood and the vessel wall is of great clinical interest in studying cardiovascular diseases, the major causes of death in developed countries.Objective: To understand the effects of incorporating fluid-structure interaction into the simulation of blood flow through an anatomically realistic model of abdominal aorta and renal arteries reconstructed from CT...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2003